Chemical modifications of bafilomycin-type 16-membered dienlactone macrolides.
نویسندگان
چکیده
Derivatives of the 16-membered dienlactone bafilomycins were prepared in order to study the structure-activity relationship of these compounds. Some derivatives formed by hydrolysis, O-alkylation, O-acylation, trans-esterification and epoxidation were isolated and their structures determined by two-dimensional (2D) NMR studies and mass spectroscopy.
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عنوان ژورنال:
- The Journal of antibiotics
دوره 40 3 شماره
صفحات -
تاریخ انتشار 1987